Based upon the nature of Celiac Disease and its relationship with the immune system, it seems that some people with Celiac Disease are not adequately protected by the Hepatitis B vaccine. Here is an excerpt from About.com’s post:
When you receive the hepatitis B vaccine series, your immune system is supposed to respond by producing antibodies to the hepatitis B virus. In addition, some of the immune cells that are involved in the body’s response to the vaccine become what’s known as “memory cells.” Many studies have shown, however, that in patients with celiac disease, the vaccine does not always produce adequate (or “protective”) levels of antibodies or memory cells.
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