The cause of Celiac Disease (also known as celiac sprue or gluten-sensitive enteropathy) is currently unknown, however, research indicates that Celiac Disease is strongly associated with a group of genes on Chromosome 6. These genes (HLA class II) are involved in the regulation of the body’s immune response to gluten protein fractions.
Recent studies have shown that an amazing 1 out of 133 people in the United States suffers from Celiac Disease! Studies have also shown that Celiac occurs in 5-15% of the offspring and siblings of a person with Celiac Disease. Research also suggests that in 70% of identical twins, both twins have the disease. It is strongly suggested that family members be tested, even if asymptomatic. Family members who have an autoimmune disease are at a 25% increased risk of having Celiac Disease.
For additional information, check out our Celiac Information page!
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