For adults with Celiac Disease or other intestinal diseases, one of the things that you are at high risk for is Urinary Stone Disease (USD). I just noticed that recently a study was done on adults with USD and Celiac Disease, which was documented over at Jurology.
For their study, they took patients who were 18 years or older, untreated, and also newly diagnosed with celiac disease by serum markers and jejunal biopsy. Clinical presentation of celiac disease was assessed focusing on 5 disorders of diarrhea, and deficiency of calories (low body mass index or weight loss), lipid (low prothrombin time or low serum lipids), iron (low hemoglobin or low serum ferritin), and calcium (low serum calcium or low bone densitometry). Urinary stone disease history was also assessed via questionnaire (imaging, stone excretion, stone disruption/removal), and urinary variables were measured in a 24-hour collection in a subgroup of patients.
Here is an excerpt of their findings:
Study Results
Under untreated conditions (baseline) urinary stone disease was independent of celiac disease presentation and more prevalent in patients with celiac disease than in a population sample used as a control (608 and 3,540, 7.9% and 5.0%, sex and age adjusted odds ratio 4.0, 95% CI 2.7–5.9). Excluding from analysis individuals with baseline urinary stone disease, the incidence of urinary stone disease history was not significantly different between the treated celiac disease (gluten-free diet) and control population (458 and 3,003, 2.4% vs 3.9%). The urine of untreated patients with celiac disease differed from that of healthy volunteers with 120% higher oxalate and 43% lower calcium (in 45 and 45, p <0.001). A gluten-free diet corrected urinary abnormalities (p <0.01).
If you’d like to learn more, click over to read the rest of their post!
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